VA RESEARCH ON DEMENTIA -- Study finds physical
failings precede dementia.

Story here...
http://seattletimes.nwsource.com/html/localnews/2003012586_dementia23m.html
Story below:
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Group Health study finds physical failings
precede dementia
By Warren King
Seattle Times medical reporter
The earliest signs of dementia may not involve a decline in mental functions
after all.
Instead, they're probably physical — a slowed gait, a failing sense of
balance and a weakened handgrip, Seattle researchers have found.
In fact, older people who have those problems have triple the risk of
dementia, including Alzheimer's disease, than those without those problems,
according to the scientists from Group Health Cooperative, the Veterans
Administration and the University of Washington.
"In aging, you don't want to separate the physical from the cognitive,
because they are inextricably linked," said Dr. Eric Larson, the lead
scientist in the research and director of the Center for Health Studies at
Group Health.
"And if you can improve one, you're likely to improve the other, and vice
versa."
The study by Larson, Li Wang of the VA Puget Sound Health Care System and UW
researchers is the largest done on the physical precursors to dementia. It
is reported in the current issue of Archives of Internal Medicine; it was
funded by the National Institute on Aging.
The researchers kept tabs on nearly 2,300 Group Health members age 65 and
older for six years, giving them physical and mental exams every two years.
None had dementia at the start of the study. After six years, 319, or about
14 percent, had dementia, including 221 with Alzheimer's.
Overall, participants who had problems with their physical functioning at
the beginning of the study had an increased risk of developing dementia and
showed increased cognitive decline during the six years.
Specifically, poor standing balance and slowed walking were linked to an
increased dementia risk. A poor handgrip was linked to the increased risk
among people with possible mild cognitive problems.
More research is needed to confirm the findings and better understand them,
the researchers said. But the scientists speculated in the report that
"physical decline and cognitive decline may be inseparable during the
development of dementia."
Previous research has shown that certain changes in the brain will affect
both motor function and the hippocampus, a part of the brain that is the
center of memory and closely associated with Alzheimer's.
Larson said no one knows precisely how long brain degeneration goes on
before dementia becomes apparent. But many scientists believe it can take 10
years or longer. And research has shown that something can be done about it.
A study published by Larson and colleagues last January, for example, found
that moderate exercise can delay dementia for many older adults, and the
frailest may benefit the most.
Exercise improves blood flow to the brain, so brisk walks — even a couple of
15-minute strolls a day — can help a lot, Larson said.
"It's key that you don't assume you get enough exercise through everyday
activities," he said. "You have to really exercise daily, just like you have
to brush your teeth daily."
Exercising the mind — including reading, doing crossword puzzles, playing
bridge — also helps stave off dementia, other research has shown.
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Larry Scott
(go
back to VA Watchdog dot Org Home Page)
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