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from Larry Scott at VA Watchdog dot Org -- 01-03-2007 #1
 


 

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PTSD SUFFERERS AT GREATER RISK OF HEART ATTACK AND

HAVE REDUCED PAIN SENSITIVITY -- Two landmark

studies shed new light on health problems

for those with stress disorder.

 

 

We have two stories.

The first is about PTSD and risk of heart attacks...the second is about PTSD and reduced pain sensitivity.

First story here... http://www.washingtonpost.com/wp-dyn/
content/article/2007/01/01/AR2007010100456.html

Story below:

---------------

`Study: War Trauma May Raise Heart Risks

By CARLA K. JOHNSON
The Associated Press



CHICAGO -- A groundbreaking study of 1,946 male veterans of World War II and Korea suggests that vets with symptoms of post-traumatic stress disorder are at greater risk of heart attacks as they age.

The new study is the first to document a link between PTSD symptoms and future heart disease, and joins existing evidence that vets with PTSD also have more autoimmune diseases such as arthritis and psoriasis.

A second study, funded by the Army, found that soldiers returning from combat in Iraq with post-traumatic stress disorder reported worse physical health, more doctor visits and more missed workdays. The Army study is based on a survey of 2,863 soldiers one year after combat.

"The burden of war may be even greater than people think," said the first study's lead author, Laura Kubzansky of the Harvard School of Public Health, who studies anxiety, depression and anger as risk factors for heart disease. Her work, with colleagues from Harvard and Boston University, appears in Monday's Archives of General Psychiatry.

Their study was funded by the National Institutes of Health and the Department of Veterans Affairs. The Army study appears in Monday's American Journal of Psychiatry.

The possible link with heart disease didn't surprise one Iraq veteran diagnosed with PTSD.

"It didn't take a rocket scientist to figure out," said John Oliveira of New Bedford, Mass., a former Navy public affairs officer and veteran of Iraq and Afghanistan. "It should also be a wake-up call that the cost to treat those of us suffering from PTSD could dramatically increase as we age."

Medical authorities first accepted post-traumatic stress disorder as a psychiatric condition in 1980 at the urging of Vietnam veterans.

In PTSD, the body's normal hormonal response to stress becomes trigger-happy, scientists believe. Long after traumatic events, people remain edgy, fearful and prone to nightmares and flashbacks. The continual release of adrenaline prompted by these symptoms may wear down the cardiovascular system, Kubzansky said.

"It's not enough to simply welcome them home and do some immediate evaluation or help with reintegration," she said. "They need to be tracked and watched carefully."

The Harvard and Boston University researchers analyzed data from the Veterans Administration Normative Aging Study, a long-term research project tracking Boston-area vets.

They looked at health records of men who completed either a 46-item questionnaire measuring PTSD symptoms in 1986, or a different 35-item PTSD assessment in 1990. Both questionnaires are recognized tools for diagnosing PTSD and ask about symptoms such as sleep problems, nightmares, numbness, a heightened sense of being on guard and intrusive memories of traumatic events.

Over the 10 to 15 years after completing the questionnaires, the vets with more PTSD symptoms were more likely to have heart attacks. For each level increase in symptoms on the 1990 assessment, the risk of heart attack or chest pain rose 18 percent _ even after the researchers took into account known heart disease risk factors such as smoking, alcohol use and high blood pressure.

Although the men had different levels of PTSD symptoms, very few had enough symptoms for a true diagnosis, Kubzansky said. The study needs to be repeated to see if the findings hold true for PTSD-diagnosed veterans, and for women, she said.

The data also didn't track how frequently the men exercised, so researchers couldn't tell if the men with PTSD symptoms were getting more or less exercise than other veterans.

Dr. Gary J. Kennedy, director of geriatric psychiatry at Montefiore Medical Center, called the study "impressive." He said one symptom of PTSD is avoiding activity, which could account for some of the effect on the heart.

Kennedy, who was not involved in the study, said treatment options for PTSD include drugs, talk therapy and behavioral changes such as getting more exercise and taking action to solve small problems in life rather than shutting down emotionally.

"We've got a whole generation of veterans coming back (from Iraq and Afghanistan) and their health needs are just going to be tremendous," Kennedy said.

___

On the Net:

Archives of General Psychiatry: http://archpsyc.ama-assn.org/

---------------

Second story here... http://psychcentral.com/
news/2007/01/02/ptsd-alters-pain-response/

Story below:

---------------

PTSD Alters Pain Response

By: Psych Central News Editor

Reviewed by: John M. Grohol, Psy.D.



Scientists discover patients with posttraumatic stress disorder (PTSD) are less sensitive to pain, a finding that may be related to altered pain processing in the brain. Dutch researchers used functional brain imaging along with psychophysical assessment as individuals rated the pain they experienced from variable and fixed temperatures applied to their hands.

The research is reported in the January issue of the Archives of General Psychiatry, one of the JAMA/Archives journals.

Posttraumatic stress disorder (PTSD) is an anxiety disorder that may occur in individuals exposed to a traumatic event. It is characterized by chronic arousal, re-experience of the event, and avoidance of stimuli related to the event, according to background information in the article. To the authors’ knowledge, no functional imaging study has explored whether patients with PTSD experience and process pain in a different way than control subjects.

Elbert Geuze, Ph.D., of Central Military Hospital and the Rudolph Magnus Institute of Neuroscience, Utrecht, the Netherlands, and colleagues conducted a study to examine neural correlates of pain processing in patients with PTSD. Twelve male Dutch veterans with PTSD and 12 male veterans without PTSD were recruited and matched for age, region of deployment and year of deployment.

The experimental procedure consisted of psychophysical assessment and neuroimaging with functional magnetic resonance imaging (fMRI)–the use of magnetic resonance imaging to learn which regions of the brain are active in a specific function. During fMRI, the patients rated the pain they experienced from fixed and variable temperatures applied to their hands.

“Patients with PTSD rated temperatures in the fixed-temperature assessment as less painful compared with controls,” the authors report.

“Before fMRI, patients with PTSD already showed a significant reduction in pain sensitivity,” the authors write. “During imaging, patients with PTSD rated a fixed temperature as significantly less painful than control veterans.” Patients with PTSD showed altered pain processing in brain areas associated with mood and cognitive pain processing.

“These data provide evidence for reduced pain sensitivity in PTSD. The witnessed neural activation pattern is proposed to be related to altered pain processing in patients with PTSD,” the authors conclude.

Source: http://archpsyc.ama-assn.org/

---------------

Larry Scott

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